Data Scientist / Engineer - DNA-Encoded Library Technology (DELT)

The requirements

  • PhD or M.S. in Bioinformatics, Statistics, Computer Science, Data Science, Cheminformatics, Software Engineering, or a related quantitative field
  • Strong software engineering background with experience deploying pipelines at scale in HPC or cloud platforms
  • Proven experience in high-throughput scientific data analysis, preferably with large-scale screening data, DEL selection outputs, or NGS processing pipelines
  • Demonstrated ability to architect reliable, user-friendly tools simplifying complex analytical workflows for non-expert scientists
  • Strong proficiency in Python and statistical programming
  • Expertise in data visualization frameworks (e.g., Spotfire, Tableau, or modern web dashboarding tools)
  • Understanding of hit-triaging, noise reduction, statistical ranking, and signal verification in large-scale datasets
  • Capability in cheminformatics, including handling chemical structures, building-block metadata, or toolkits like RDKit/OpenEye
  • Knowledge of laboratory data systems (LIMS, SQL, relational databases) and integrating computational tools with experimental workflows is a plus
  • Critical thinker and problem solver with a continuous improvement mindset
  • Strong communication skills to translate complex quantitative findings for multidisciplinary and non-quantitative stakeholders

What you'll be doing

  • Advance DELT data analytics by applying statistical methods, predictive models, and advanced analytical approaches on large-scale DEL screening datasets
  • Develop intuitive, accessible analytical tools and workflows to empower DELT screening scientists and project teams in evaluating selection results and prioritizing compounds
  • Design, implement, and maintain automated and reproducible data processing and analysis pipelines for transforming complex experimental outputs into trusted insights
  • Create computational workflows and searchable building-block data resources to support chemical space exploration, reaction prediction, library design, and synthesis strategy optimization
  • Collaborate with experimental scientists, computational chemists, and machine learning teams to translate scientific challenges into scalable computational solutions
  • Communicate scientific insights and technical developments clearly to scientific and multidisciplinary audiences to support knowledge sharing and adoption
  • Promote scientific excellence through reproducibility, data integrity, robust engineering practices, and contribute to a safe and compliant research environment

Nice to haves

  • Experience integrating computational tools with experimental workflows
  • Familiarity with laboratory data systems such as LIMS, SQL, and relational databases
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